United Physicians was founded in 2000 through the merger of Beaumont Physician Group Royal Oak and Beaumont Physician Group Troy. Forerunning organization, Premier Physicians Network (PPN), was founded in 1996 as an HMO contracting entity for these two physician organizations. In 2012, PPN was merged into United Physicians. Members have medical staff privileges at hospitals and health systems including:
- Beaumont Health System
- Botsford General Hospital
- Crittenton Hospital Medical Center
- Detroit Medical Center
- Doctors Hospital of Michigan
- Garden City Hospital
- Genesys Regional Medical Center
- Henry Ford Health System
- Hurley Medical Center
- Ingham Regional Medical Center
- Lapeer Regional Medical Center
- McLaren Regional Medical Center
- Oakwood Healthcare System
- St. John Health
- St. Joseph Mercy Hospital